Transcutaneous Auricular Vagus Nerve Stimulation Protects Endotoxemic Rat from Lipopolysaccharide-Induced Inflammation

Figure 5

VNS or ta-VNS suppresses LPS-induced NF-κB expression; ST36 stimulation did not affect NF-κB in endotoxemia animals significantly. ta-VNS did not significantly affect pulmonary NF-κB expression with normal saline administration. NF-κB expressions were measured by western blot technique. Data are shown by mean ± SEM (𝑛=12 per group). ^▵▵𝑃<0.01 versus normal saline (NS) group; ^∗∗𝑃<0.01 versus LPS group (LPS); ^##𝑃<0.01 versus LPS+VNS group; ^▴𝑃<0.05 versus LPS+ ta-VNS.