Review Article

Clinical Efficacy and Safety of Buyang Huanwu Decoction for Acute Ischemic Stroke: A Systematic Review and Meta-Analysis of 19 Randomized Controlled Trials

Table 4

Meta-analyses of the total effective rate of BHD therapy for acute ischemic stroke.

Study or subgroupExperimentalControlWeightRisk ratioRisk ratio
EventsTotalEventsTotalM-H, random, 95% CIM-H, random, 95% CI

Chen, 2007 [32]283221323.0%1.33 [1.00, 1.77]630124.tab.002
Cui et al.,2005 [34]495025306.6%1.18 [1.00, 1.39]
Fang et al.,2005 [27]586547725.5%1.37 [1.13, 1.65]
Guo, 2009 [25]565727309.1%1.09 [0.96, 1.24]
Jia et al.,2010 [26]303221284.1%1.25 [0.99, 1.58]
Kang, 2006 [30]3536353810.4%1.06 [0.95, 1.18]
Lin, 2008 [31]303222304.0%1.28 [1.01, 1.61]
Liu, 2010 [35]525540556.2%1.30 [1.09, 1.55]
Lv, 2009 [39]333530357.0%1.10 [0.94, 1.29]
Run, 2001 [37]212414241.8%1.50 [1.04, 2.17]
Shi and Zhang,1995 [36]172112201.5%1.35 [0.89, 2.04]
Wang and Yu,2005 [38]6264556410.4%1.13 [1.01, 1.26]
Wu and Luo,2011 [23]333529356.3%1.14 [0.96, 1.35]
Yan and Mei,2004 [33]556052609.1%1.06 [0.93, 1.20]
Zhang, 2004 [24]364025403.4%1.44 [1.11, 1.87]
Zhang et al.,2010 [12]778267829.7%1.15 [1.02, 1.29]
Zheng et al.,2004 [40]242713221.8%1.50 [1.04, 2.18]
Total (95% CI)747697100.0%1.18 [1.12, 1.24]
Total events696535
Heterogeneity: Tau² = 0.00; Chi² = 24.82, df = 16 (P = 0.07); = 36%
Test for overall effect: Z = 6.02 (P < 0.00001)