Ficus deltoidea: A Potential Alternative Medicine for Diabetes Mellitus

Table 4

Effect of F. deltoidea extracts on adiponectin secretion from 3T3F442A adipocytes.

	Fold of glucose uptake against control
Extract concentration (μg/mL)	Control	100 nM insulin	Hot aqueous		Ethanolic		Methanolic		Rosiglitazone malate
			Basal	Insulin-mediated	Basal	Insulin-mediated	Basal	Insulin-mediated	Basal	Insulin-mediated
10			1.01	0.93	1.06	0.99	1.11	1.45***	70 μM; 3.10***; •••	3.5 μM; 2.93***; •••
50			1.16	1.05	0.99	1.04	1.09	1.46***
100	1.00	1.64***	1.20	1.21	1.04	1.12	1.28	1.53***
500			2.06***; •••	1.48***	1.05	1.15	1.30*	1.67***
1000			2.46***; •••	2.10***; •••	1.17	1.24	1.53***	1.70***

Values expressed as means ± standard deviations from three independent experiments.
^∗𝑃<0.05, ^∗∗∗𝑃<0.001 compared with control incubation.
^•••𝑃<0.001 compared to 100 nM insulin.