A Herbal Composition of Semen Hoveniae, Radix Puerariae, and Fructus Schisandrae Shows Potent Protective Effects on Acute Alcoholic Intoxication in Rodent Models
Table 4
Effects of SRFE on activities of antioxidative enzymes and content of MDA in the liver of acutely inebriated mice.
Groups
Doses
Ethanol
SOD
CAT
GPx
GST
MDA
(g/kg)
(g/kg)
(U/mg prot)
(U/mg prot)
(U/mg prot)
(U/mg prot)
(mol/g prot)
Control
—
0.00
245 ± 7
85 ± 2
386 ± 17
55 ± 3
1.20 ± 0.03
SRFE control
0.24
0.00
245 ± 5
84 ± 3
424 ± 14
57 ± 2
1.15 ± 0.04
Model
—
7.70
203 ± 6##
74 ± 3#
318 ± 13 ##
37 ± 2##
1.33 ± 0.03#
SRFE
0.06
7.70
226 ± 6*
89 ± 2**
356 ± 11*
49 ± 2**, #
1.23 ± 0.04
0.12
7.70
225 ± 6*
88 ± 3 **
325 ± 17#
46 ± 2**, #
1.16 ± 0.06*
0.24
7.70
230 ± 5**
91 ± 3 **
376 ± 13 **
46 ± 3**, #
1.14 ± 0.04**
HWJZ
0.40
7.70
228 ± 7*
88 ± 4**
315 ± 21#
44 ± 3*, #
1.24 ± 0.05
SRFE: Semen Hoveniae, Radix Puerariae, and Fructus Schisandrae extract; HWJZ: Hai-Wang-Jin-Zun tablet; SOD: superoxide dismutase; CAT: catalase; GPx: glutathione peroxidase; GST: glutathione S-transferase; MDA: malondialdehyde. Means ± S.E.M., . , versus control. , versus model.
