Research Article
Chemical Composition and In Vitro Cytotoxic Activity of Essential Oil of Leaves of Malus domestica Growing in Western Himalaya (India)
Table 2
In vitro cytotoxicity against different cancer cell lines by SRB assay.
| Sample | Conc. (μg/mL) | Growth inhibition percentage | C-6 | A-549 | CHOK1 | THP-1 |
| Essential oil of leaves of M. domestica | 100 | 5.5 | 11.5 | 0 | 0 | 300 | 18.8 | 1.5 | 13.5 | 19.9 | 1000 | 58.5 | 60.7 | 68.3 | 65.7 | 1500 | 68.0 | 74.5 | 70.8 | na | 2000 | 98.2 | 76.7 | 69.5 | na | Mitomycin C | (1 μM) | 65.7 | 76.4 | 75.4 | na | Vinblastin | (1 μM) | na | na | na | 73.1 |
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na: the activity was not done.
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