Guizhi-Fuling-Wan, a Traditional Chinese Herbal Medicine, Ameliorates Memory Deficits and Neuronal Apoptosis in the Streptozotocin-Induced Hyperglycemic Rodents via the Decrease of Bax/Bcl2 Ratio and Caspase-3 Expression

Figure 2

Schedule of drug treatment and experiment orders. GFW was administrated orally daily for 7 days and 1 h prior to MWM. On days 21–24 after STZ injection in mice, the spatial memory test (SMT) of the Morris water maze (MWM) was performed 4 trials a day for 4 consecutive days, followed 24 h later (day 25) by the reference memory test (RMT). On day 21, rats were sacrificed after being administrated orally GFW 1 h later.