Mechanism of Earthquake Simulation as a Prenatal Stressor Retarding Rat Offspring Development and Chinese Medicine Correcting the Retardation: Hormones and Gene-Expression Alteration
Table 5
KEGG Pathway annotation of the 120 differentially expressed genes (, ) ( refers downregulation, refers upregulation).
Name
Symbol
Total
Percent
Enrichment test value
value
Oocyte meiosis
Itpr1↑ Ppp2r5e↑
116
0.0345
0.0008
0.0048
Cdk2↑
Vascular smooth muscle contraction
Ppp1r12a↑
128
0.0313
0.0011
0.0048
Itpr1↑
Ppp1r12b↑
RIG-I-like receptor signaling pathway
Irf7↓ Dhx58↓
64
0.0469
0.0016
0.0048
Mavs↓
Long-term potentiation
Ppp1r12a↑ Itpr1↑
72
0.0417
0.0022
0.0049
Itpr2↑
Ubiquitin mediated proteolysis
Ube2n↓ Herc1↑
132
0.0227
0.0111
0.0176
Cul5↑
Cytosolic DNA-sensing pathway
Irf7↓ Mavs↓
49
0.0408
0.0131
0.0176
Biotin metabolism
Hlcs↓
3
0.3333
0.0135
0.0176
RNA degradation
Cnot6↑ Dcp1a↑
61
0.0328
0.0196
0.0223
Long-term depression
Itpr1↑ Itpr2↑
69
0.029
0.0245
0.0245
Ubiquinone and other terpenoid-quinone biosynthesis
