Gallic Acid Attenuates Platelet Activation and Platelet-Leukocyte Aggregation: Involving Pathways of Akt and GSK3β

Figure 4

Effects of gallic acid on intracellular Ca²⁺ concentration of platelets measured by flow cytometry. Gallic acid at a concentration of 100 μM and 500 μM inhibited the intracellular Ca²⁺ rise, which were stimulated by (a) ADP (10 μM) and (b) U46619 (2 μM). These results were confirmed in 3 separate experiments. GA: gallic acid.

(a)

(b)