Review Article

Outcome Measures of Chinese Herbal Medicine for Hypertension: An Overview of Systematic Reviews

Table 1

Outcome measures of CHM for hypertension in systematic reviews.

Outcome measures (number of SR)Condition (number of SR)CHMFirst authorNumber of RCTs/totalConclusionRisk of publication bias

Primary endpoints

Mortality, stroke, coronary heart disease, and hypertensive renal damage (1)Essential hypertension (1)Niuhuang Jiangya preparationWang et al. (2008) [27]3/3BNA
hypertensive renal damage (1)Elderly hypertension (1)Herbal productsHan (2012) [36]4/45ANA

Secondary endpoints

Blood pressure (10)Essential hypertension (8)Niuhuang Jiangya preparationWang (2008) [27]3/3BNA
Herbal productsHu (2009) [28]24/24AL
Herbal productsRen (2006) [29]11/11AH
Tianma Gouteng YinDong (2011) [30]6/6AL
Tianma Gouteng YinZhang (2012) [31]0/0BNA
Pinggan qianyangXu (2012) [32]8/8AH
Buyi shenqiShi (2012) [33]5/5AH
Buyi pishenLiu (2011) [34]13/15AL
Elderly isolated systolic hypertension (1)Herbal productsLi (2012) [35]17/17AL
Elderly hypertension (1)Herbal productsHan (2012) [36]45/45ANA
Triglycerides (1)Essential hypertension (1)Herbal productsHu (2009) [28]4/24AL
Pulse pressure (1)Elderly isolated systolic hypertension (1)Herbal productsLi (2012) [35]4/17AL
Quality of life (1)Elderly hypertension (1)Herbal productsHan (2012) [36]4/45ANA
TCM syndrome (5)Essential hypertension (3)Pinggan qianyangXu (2012) [32]3/8AH
Buyi shenqiShi (2012) [33]4/5AH
Buyi pishenLiu (2011) [34]9/15AL
Elderly isolated systolic hypertension (1)Herbal productsLi (2012) [35]6/17AL
Elderly hypertension (1)Herbal productsHan (2012) [36]4/45ANA

Notes: Pinggan qianyang: calming the liver and suppressing liver-yang to patients with hyperactivity of liver yang syndrome; Buyi shenqi: replenishing kidney qi to patients with kidney qi deficiency syndrome; Buyi pishen: replenishing spleen and kidney to patients with spleen and kidney deficiency syndrome; A: CHM may be or appear to be effective; B: the evidence is insufficient and inclusive; H: high; L: low; NA: not mentioned.