Table 3: The depletion analyses of proteins with the highest degree/betweenness centrality among top 0.1% and top 1% candidate target-genes.

Lower-tailed values of hypergeometric cumulative distribution
Top 0.1% candidate targetsTop 1% candidate targets

The proteins with the highest degree
The proteins with the highest betweenness centrality

The proteins with the highest degree/betweenness centrality are referred to as those with top 5% degree/betweenness centrality in the protein interaction network.