Acute and Chronic Administrations of Rheum palmatum Reduced the Bioavailability of Phenytoin in Rats: A New Herb-Drug Interaction
Figure 3
Effects of RP (2.0, 1.0 and 0.5 mg/mL) and verapamil (Ver, 100 μM as a positive control of P-gp inhibitor) on the accumulation of PHT in LS 180 cells. Data expressed as mean ± S.D. of four determinations. *.
