Acute and Chronic Administrations of Rheum palmatum Reduced the Bioavailability of Phenytoin in Rats: A New Herb-Drug Interaction
Figure 4
Effects of indomethacin (Indo) on the intracellular accumulation of PHT ((a), 10 μM) and HPPH ((b), 10 μM) in MDCKII and MDCKII-MRP 2 cells. Data expressed as mean ± S.D. of four determinations. *.