A Therapeutic Approach for Wound Healing by Using Essential Oils of Cupressus and Juniperus Species Growing in Turkey
Table 3
Effects of the essential oils from C. sempervirens var. horizontalis, C. sempervirens var. pyramidalis, J. communis, J. excelsa, J. foetidissima, J. oxycedrus, and J. phoenicea on circular excision wound model.
Material
Wound area ± SEM (contraction %)
0
2
4
6
8
10
12
Vehicle
19.55 ± 2.09
17.98 ± 2.20 (2.55)
16.54 ± 2.11 —
14.89 ± 1.95 —
9.55 ± 1.56 (9.51)
6.31± 1.16 (8.42)
2.97 ± 0.87 (5.41)
Negative Control
19.43 ± 2.15
18.45 ± 2.23
16.42 ± 2.17
14.72 ± 1.91
10.51 ± 1.75
6.89 ± 1.23
3.14 ± 1.49
C. sempervirens var. horizontalis
19.40 ± 2.13
17.56 ± 1.40 (2.34)
16.02 ± 1.50 (3.14)
14.91 ± 1.62 —
9.57 ± 1.40 —
5.86 ± 1.32 (7.13)
3.56 ± 0.69 —
C. sempervirens var. pyramidalis
20.03 ± 2.12
17.90 ± 1.91 (0.44)
16.69 ± 1.92 —
14.92 ± 1.60 —
8.84 ± 1.67 (7.43)
7.08 ± 1.12 —
2.59 ± 0.84 (12.79)
J. communis subsp. nana Syme.
19.55 ± 2.22
17.81 ± 1.81 (5.56)
16.75 ± 1.80 —
15.16 ± 1.87 —
9.57 ± 1.74 —
6.02 ± 0.99 (4.60)
3.04 ± 0.89 —
J.excelsa
19.50 ± 2.16
14.99 ± 1.78 (16.63)
13.24 ± 2.09 (19.95)
11.26 ± 1.70 (24.38)
7.39 ± 1.58 (22.62)
5.47 ± 1.07 (13.31)
2.44 ± 0.90 (17.85)
J. foetidissima
19.96 ± 2.51
16.16 ± 1.89 (10.12)
14.02 ± 1.78 (15.24)
13.49 ± 1.71 (9.40)
9.09 ± 1.54 (4.82)
6.10 ± 1.27 (3.33)
2.49 ± 1.05 (16.16)
J. oxycedrus subsp. oxycedrus
19.41 ± 2.08
17.51 ± 1.92 (2.61)
16.02 ± 1.70 (6.05)
12.62 ± 1.63 (15.25)
6.03 ± 1.03 (36.86)*
3.85 ± 0.96 (38.99)*
1.69 ± 0.60 (43.10)*
J. phoenicea
19.59 ± 2.19
16.46 ± 2.54 (8.45)
14.02 ± 1.96 (15.24)
11.97 ± 1.86 (19.61)
7.44 ± 1.39 (22.09)
4.21 ± 1.28 (33.28)*
1.76 ± 0.61 (40.74)*
Madecassol
19.68 ± 2.03
14.46 ± 1.83 (19.58)
11.77 ± 1.45 (28.84)
8.76 ± 1.21 (41.17)**
4.74 ± 0.89 (50.37)**
2.12 ± 0.31 (66.40)***
0.00 ± 0.00 (100.00)***
*
; ** ; *** ; SEM: standard error of the mean. Percentage of contraction values: vehicle group was compared to negative control group; the oils and the reference material were compared to vehicle group.
