Antimicrobial Activity of Essential Oils against Streptococcus mutans and their Antiproliferative Effects
Table 2
Selected EO and their fractions with yield results, MIC and MBC values, and MBC : MIC ratio.
Essential oil
Fraction
Identification
MIC (μg/mL)
MBC (μg/mL)
Identification
Yield (%)
MIC (μg/mL)
MBC (μg/mL)
MBC : MIC ratio1
Aloysia gratissima (Ag)
125–250
250–500
Ag1
28.9
250–500
500–1000
2 : 1
Ag2
17.9
250–500
500–1000
2 : 1
Ag3
20.1
62.5–125
500–1000
8 : 1
Ag42
14.4
31.2–62.5
62.5–125
2 : 1
Baccharis dracunculifolia (Bd)
62.5–125
250–500
Bd1
30.5
250–500
500–1000
2 : 1
Bd2
22.1
15.6–31.2
125–250
8 : 1
Coriandrum sativum (Cs)
31.2–62.5
62.5–125
Cs1
6.6
125–250
500–1000
4 : 1
Cs2
4.9
125–250
250–500
2 : 1
Cs3
12.7
15.6–31.2
31.2–62.5
2 : 1
Cs4
30.9
15.6–31.2
31.2–62.5
1 : 1
Lippia sidoides (Ls)
62.5–125
125–250
Ls1
13.6
250–500
500–1000
2 : 1
Ls2
33.3
62.5–125
250–500
4 : 1
Ls3
26
62.5–125
125–250
2 : 1
Ls4
6.1
62.5–125
125–250
2 : 1
Ls5
1.7
62.5–125
125–250
2 : 1
1 The fractions from selected EO were considered bactericidal when the MBC : MIC ratio was between 1 : 1 to 2 : 1, and bacteriostatic if this ratio was higher than 2 : 1. 2 The fractions in bold font were selected as active fractions and evaluated against S. mutans biofilm and for their antiproliferative action. The subscript numbers of the fractions represent the numbers of parts obtained using the dry column fractionation.
