Research Article
Effects of Rhizophora mangle on Experimental Colitis Induced by TNBS in Rats
Table 2
Effects of BuOH fraction and EtOAc fraction on parameters observed in colon of rats submitted to colitis induced by TNBS.
| | Group | n | Score | Lesion (cm) | Weigh/length
(mg/cm) | Adhesion | Diarrhea |
| | Noncolitic | 6 | 0*** | 0*** | 91.6 ± 2.5*** | 0*** | 0*** | | Colitic nontreated | 10 | 9.2 ± 0.6 | 5.5 ± 0.8 | 225.6 ± 56.7 | 1.5 ± 0.5 | 1.0 ± 0.0 | | BuOH fraction 0.5 mg/Kg | 10 | 8.1 ± 0.8* | 4.3 ± 0.8* | 217.8 ± 18.0 | 0.4 ± 0.6** | 0.7 ± 0.4 | | EtOAc fraction 1.5 mg/Kg | 9 | 8.3 ± 1.0 | 4.4 ± 1.3* | 227.3 ± 40.2 | 1.0 ± 0.7 | 0.7 ± 0.4 |
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Results are presented as mean ± SEM ANOVA followed by Dunnett’s t-test, *, **, *** significantly different from colitic nontreated.
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