Table 5: Effect of BuOH fraction and EtOAc fraction on colonic TNF-α, IL-6, IL12, and IL-10 levels in TNBS-induced colitis in rats.

GroupColon TNF-α levels
(pg/mg of protein)
Colon IL-6 levels
(pg/mg of protein)
Colon IL-12 levels
(pg/mg of protein)
Colon IL-10 levels
(pg/mg of protein)

Noncolitic 357.3 ± 20.7***209.1 ± 24.3***12.7 ± 1.9***295.0 ± 37.7***
Colitic nontreated1381.0 ± 227.5807.3 ± 45.528.5 ± 2.4120.4 ± 4.3
BuOH fraction 0.5 mg/Kg469.5 ± 21.5***719.1 ± 17.416.72 ± 1.0***152.5 ± 11.6
EtOAc fraction 1.5 mg/Kg567.9 ± 21.8***615.4 ± 54.4**19.09 ± 1.7**252.1 ± 19.3**

Results are presented as mean ± SEM ANOVA followed by Dunnett’s t-test, * , ** , *** significantly different from colitic nontreated.