Antiasthmatic Effects of Herbal Complex MA and Its Fermented Product MA128

Figure 5

Cytokines, eotaxin, and ovalbumin-immunoglobulin E production in bronchoalveolar lavage fluid, OVA-specific splenocytes culture supernatant, and serum. (a), (b), and (c) Effect of MA and MA128 on Th2 cytokines (IL-5, IL-13), Th1 cytokine (IL-17), eotaxin in BALF and OVA-specific IgE in serum; (d) immunomodulatory effects of MA and MA128 on OVA-specific Th1/Th2 cytokines production in spleen cells (described in Section 2). Results are expressed the mean ± S.E. (𝑁=8). Statistical significance between control and treatment groups was assessed by ANOVA (*𝑃<0.05, **𝑃<0.01, significant increase; *𝑃<0.05). Normal: normal Balb/c mice, OVA-CT: Ovalbumin inhalation + vehicle, OVA + CsA (10 mg/kg), OVA + MA (300 mg/kg), OVA + MA128 (300 mg/kg).

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