Emodin, a Naturally Occurring Anthraquinone Derivative, Ameliorates Dyslipidemia by Activating AMP-Activated Protein Kinase in High-Fat-Diet-Fed Rats
Figure 1
Changes in the hepatic cholesterol and triglyceride in HFD-fed rats receiving 8-week treatment. Rats not receiving any treatment were given the same volume of vehicle (distilled water) used to dissolve the test medications. Hepatic lipids were analyzed from vehicle-treated RCD-fed rats, vehicle-treated HFD-fed rats, emodin- (40 mg kg−1 per day) treated HFD-fed rats- (emodin 40), emodin- (80 mg kg−1 per day) treated HFD-fed rats (emodin 80) or pioglitazone (20 mg kg−1 per day)-treated HFD-fed rats (pioglitazone). Values (mean ± SEM) were obtained from each group of 8 animals in each group after 8 weeks of the experimental period. compared to the values of vehicle-treated HFD-fed rats in each group, respectively.
