Emodin, a Naturally Occurring Anthraquinone Derivative, Ameliorates Dyslipidemia by Activating AMP-Activated Protein Kinase in High-Fat-Diet-Fed Rats
Figure 2
Histopathological findings in livers of HFD-fed rats receiving 8-week treatment. Rats not receiving any treatment were given the same volume of vehicle (distilled water) used to dissolve the test medications. Photomicrographs are of tissues isolated from vehicle-treated RCD-fed rats (vehicle-RCD), vehicle-treated HFD-fed rats (vehicle-HFD), emodin- (40 mg kg−1 per day) treated HFD-fed rats- (emodin 40-HFD), emodin (80 mg kg−1 per day) treated HFD-fed rats (emodin 80-HFD) or pioglitazone- (20 mg kg−1 per day) treated HFD-fed rats (pioglitazone-HFD). Photomicrographs were taken at a magnification of x400.