The Components of Flemingia macrophylla Attenuate Amyloid β-Protein Accumulation by Regulating Amyloid β-Protein Metabolic Pathway

Figure 4

The effects of the fractions and flavonoids of F. macrophylla on Aβ1-40 degradation in the N2a-conditioned medium. Aβ1-40 (10 ng) were incubated in the N2a-conditioned medium with 100 nM insulin and the fractions and flavonoids of F. macrophylla at NTC, 37°C for 20 h. The level of remaining Aβ1-40 was determined by ELISA. Results are means ± SD from three independent experiments. Significant differences between control and the treated cells are indicated by **𝑃<0.01, ***𝑃<0.001.