Antirheumatoid Arthritis Activities and Chemical Compositions of Phenolic Compounds-Rich Fraction from Urtica atrichocaulis, an Endemic Plant to China

Table 4

Effect of phenolic compounds-rich fraction from Urtica atrichocaulis (TFUA) on the mice pain induced by hot-plate.

Group	Dose (mg/kg)	Anterior pain threshold (s)	Posterior pain threshold (s)
			30	60	90	120
Vehicle	—	18.0  ±  3.5	20.1  ±  5.7	21.5  ±  5.6	21.2  ±  6.7	19.9  ±  8.1
Morphine	30	18.5  ±  3.5	30.4**  ±  3.8	35.0**  ±  6.0	28.6**  ±  4.1	27.4**  ±  4.6
TFUA	50	19.4  ±  3.8	21.6  ±  5.5	23.2  ±  6.1	21.7  ±  7.2	21.3  ±  8.8
	150	19.0  ±  3.7	21.2  ±  5.4	22.7  ±  5.9	21.4  ±  7.0	22.0  ±  8.5

Values are expressed as mean ± SD. N  =  10. *P  <  0.05, **P  <  0.01 compared with vehicle control.