Research Article

Antiatherosclerotic Effect of Canarium odontophyllum Miq. Fruit Parts in Rabbits Fed High Cholesterol Diet

Table 6

Plasma malondialdehyde (MDA) level in experimental rabbits.

GroupsPlasma MDA (mol/L)
Week 0Week 4Week 8

NC2.60 ± 0.04a,12.67 ± 0.08b,23.74 ± 0.15b,2
PC2.92 ± 0.32a,13.10 ± 0.17ab,14.37 ± 0.18c,2
HS (simvastatin)2.80 ± 0.10a,12.87 ± 0.07c,14.17 ± 0.17bc,2
HPO (pulp oil)2.96 ± 0.08a,13.42 ± 0.03b,23.78 ± 0.08b,3
HKO (kernel oil)3.03 ± 0.18a,13.44 ± 0.15b,13.79 ± 0.05b,2
HF (fullfat)3.06 ± 0.12a,13.06 ± 0.11b,13.70 ± 0.09b,2
HD (defatted)2.92 ± 0.18a,13.77 ± 0.09a,22.81 ± 0.04a,1

NC: normal diet group, PC: positive control, HS, HPO, HKO, HF, and HD: hypercholesterolemic group treated with 10 mg/kg/day simvastatin, 20 g kg−1 of pulp oil, 20 g kg−1 kernel oil, 50 g kg−1 fullfat pulp, or 50 g kg−1 defatted pulp, respectively. Values are expressed as mean ± SEM. Values within column followed by the same superscript letter are not significantly different at . Values within groups followed by the same superscript number are not significantly different at .