Green Tea Polyphenols for the Protection against Renal Damage Caused by Oxidative Stress

Figure 9

Western blot analyses of iNOS (A), COX-2 (B), NF-𝜅Bp65 (C), and I𝜅B-𝛼 (phosphorylated and nonphosphorylated) (D) protein expression in the renal cortex of normal rats (N) and diabetic nephrectomized rats treated with (−)-epigallocatechin 3-O-gallate at 25 mg/kg body weight/day (E25), 50 mg/kg body weight/day (E50), 100 mg/kg body weight/day (E100), or water (control, C) for 50 days. Significance: ^a𝑃<0.05, ^b𝑃<0.01, ^c𝑃<0.001 versus normal values; ^d𝑃<0.05, ^e𝑃<0.01, ^f𝑃<0.001 versus diabetic nephropathy control values.