Identification of Major Active Ingredients Responsible for Burn Wound Healing of Centella asiatica Herbs
Figure 5
Effects of asiaticoside (AD), madecassoside (MD), asiatic acid (AA), and madecassic acid (MA) on TGF-β/Smad pathway in human skin fibroblasts. ((a)–(e)) The mRNA expressions of TGF-β1, TβRI, TβRII and Smad 7 were measured viaRT-PCR assay. ((f), (g)) The phosphorylation of Smad 3 was measured via Western blot assay. Each column represents the mean ± S.D. from three independent experiments. *, ** versus control.