Proteomic Analysis Reveals the Deregulation of Inflammation-Related Proteins in Acupuncture-Treated Rats with Asthma Onset

Figure 1

Schematic localization of acupuncture points: GV14 (Dazhui), BL12 (Fengmen), and BL13 (Feishu) stimulated in rats (a), and the corresponding equivalent acupuncture points in the human body (b). (c) Presentation of the experimental procedure; rats were sensitized with OVA at day 0. Acupuncture was repeatedly administered at specific acupuncture points on alternate days for 2 weeks from the first day after sensitization. On day 14, rats were anaesthetized and challenged with OVA by injection into the external jugular vein. The pulmonary resistance (RL), dynamic compliance (Cdyn), and respiratory rate (RR) were recorded before the challenge for 10 min as the baseline values and immediately measured for another 10 min after the OVA challenge. The sample collections were performed immediately after the measurements were taken. Control rats were sensitized and challenged with saline instead of OVA.