Dentatin Induces Apoptosis in Prostate Cancer Cells via Bcl-2, Bcl-xL, Survivin Downregulation, Caspase-9, -3/7 Activation, and NF-κB Inhibition

Figure 6

Multiparameter cytotoxicity analysis of dentatin-treated PC-3 and LNCaP cell lines. Representative images of PC-3 or LNCaP cells treated with medium alone (control) or 15 μM of dentatin. Cells were stained with Hoechst 33342, cell membrane permeability dye, MMP dye, and cytochrome c antibody as described in Section 2. (Magnification at 20x.)