Dentatin Induces Apoptosis in Prostate Cancer Cells via Bcl-2, Bcl-xL, Survivin Downregulation, Caspase-9, -3/7 Activation, and NF-<i>κ</i>B Inhibition

<table>Dentatin decreases pro-survival molecules of prostate cancer cells. PC-3 and LNCaP were treated with control DMSO, control drug paclitaxel or dentatin. Cell lysates collected were resolved with SDS-PAGE gel, blotted onto membrane, and probed with antibodies against pro-survival molecules Bcl-2, Bcl-xL and Survivin. The membranes were stripped and reprobed with antibody to <i>β</i>-actin as loading control.</table>

Evidence-Based Complementary and Alternative Medicine

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Figure 9

Figure 9: Dentatin Induces Apoptosis in Prostate Cancer Cells via Bcl-2, Bcl-xL, Survivin Downregulation, Caspase-9, -3/7 Activation, and NF-<i>κ</i>B Inhibition 

Figure 9 | Dentatin Induces Apoptosis in Prostate Cancer Cells via Bcl-2, Bcl-xL, Survivin Downregulation, Caspase-9, -3/7 Activation, and NF-κB Inhibition 