Evidence-Based Complementary and Alternative Medicine / 2012 / Article / Tab 2 / Research Article
Study of the Effects of Monacolin K and Other Constituents of Red Yeast Rice on Obesity, Insulin-Resistance, Hyperlipidemia, and Nonalcoholic Steatohepatitis Using a Mouse Model of Metabolic Syndrome Table 2 NASH clinical research network scoring system.
Item Definition Score/code Low-to-medium power evaluation of parenchymal involvement by steatosis Steatosis <5% 0 5–33% 1 >33–66% 2 >66% 3 NAS Overall assessment of all inflammatory foci No foci 0 Lobular inflammation <2 foci per 200 × field 1 2–4 foci per 200 × field 2
4 foci per 200 × field 3 None 0 Hepatocellular ballooning Few balloon cells 1 Many cells/prominent ballooning 2 Full score: 8 None 0 Perisinusoidal or periportal 1 Fibrosis Stage Mild, zone 3, perisinusoidal 1A Moderate, zone 3, perisinusoidal 1B Portal/periportal 1C Perisinusoidal and portal/periportal 2 Bridging fibrosis 3 Cirrhosis 4