|
| | Deficiency of both the heart and spleen (心 脾兩 虛) | Hyperactivity of fire due to yin deficiency
(陰 虛火 旺) | Liver-qi stagnation transforming into fire
(肝 鬱化 火) | Heart-kidney noninteraction
(心 腎不 交) | Internal disturbance of phlegm heat
(痰 熱內 擾) | Qi deficiency of the heart and gallbladder
(心 膽氣 虛) | Heart deficiency with timidity
(心 虛膽 怯) |
|
| Number of studies that examined the TCM pattern | N = 64 | N = 53 | N = 43 | N = 13 | N = 34 | N = 20 | N = 15 |
| Commonly used Chinese herbal formula (N, % of studies that examined the TCM pattern) | Modified Gui Pi Tang
(19, 29.7%) | Huang Lian E Jiao Tang
(5, 9.4%) | Modified Long Dan Xie Gan Tang (6, 14.0%); Dan Zhi Xiao Yao San (6, 14.0%) | No formula was most frequently used | Modified Wen Dan Tang
(10, 29.4%) | Modified An Shen Ding Zhi Wan
(7, 35.0%) | No formula was most frequently used |
| Number of studies that provided TCM treatment principle | N = 11 | N = 9 | N = 8 | N = 1 | N = 6 | N = 5 | N = 1 |
| Most commonly used treatment principle (N, % of studies that provided TCM treatment principle) | Nourish heart and spleen (5, 45.5%) | Nourish yin and suppress fire
(5, 55.6%) | Soothe liver and purge fire
(4, 50.0%) | Nourish yin, clear fire, and coordinate heart and kidney
(1, 100.0%) | Clear heat and resolve phlegm
(5, 83.3%) | Tonify qi and settle fright
(5, 100.0%) | Tonify qi and settle fright (1, 100.0%) |
| Number of studies that provided the composition of herbal formula | N = 54 | N = 43 | N = 39 | N = 11 | N = 29 | N = 16 | N = 13 |
| Composition of herbal formula (% of studies that provided the formula’s composition)b | | | | | | | |
| Suanzaoren (Semen Z. spinosae) | 75.9% | 58.1% | 48.7% | 45.5% | 58.6% | 68.8% | 69.2% |
| Fuling (Poria) | 40.7% | 34.9% | 33.3% | 27.3% | 75.9% | 62.5% | 23.1% |
| Yejiaoteng (Caulis P. multiflori) | 33.3% | 46.5% | 41.0% | / | 41.4% | 37.5% | 61.5% |
| Gancao (Radix Glycyrrhizae) | 27.8% | 39.5% | 51.3% | / | 44.8% | 37.5% | 30.8% |
| Baishao (Radix P. alba) | 24.1% | 39.5% | 46.2% | 27.3% | 20.7% | / | 23.1% |
| Fushen (Poria cum Radix Pini) | 33.3% | 25.6% | 23.1% | / | / | 50.0% | 38.5% |
| Hehuanpi (Cortex Albizziae) | 22.2% | 34.9% | 30.8% | / | 27.6% | / | 46.2% |
| Yuanzhi (Radix Polygalae) | 53.7% | 23.3% | / | / | 41.4% | 62.5% | 38.5% |
| Wuweizi (Fructus S. Chinensis) | 24.1% | 27.9% | / | 27.3% | / | / | 38.5% |
| Baiziren (Semen Platycladi) | 20.4% | / | / | 27.3% | / | / | 23.1% |
| Shengdihuang (Radix Rehmanniae) | / | 48.8% | 30.8% | 27.3% | / | / | / |
| Danggui (Radix A. sinensis) | 63.0% | / | 51.3% | / | / | / | / |
| Dangshen (Radix Codonopsis) | 51.9% | / | / | / | / | 43.8% | / |
| Baizhu (Rhizoma A. acrocephalae) | 38.9% | / | 20.5% | / | / | / | / |
| Honey-toasted Gancao (Radix Glycyrrhizae) | 29.6% | / | / | / | / | 25.0% | / |
| Dazao (Fructus Jujibae) | 24.1% | / | / | 27.3% | / | / | / |
| Huanglian (Rhizoma Coptidis) | / | 41.9% | / | / | 51.7% | / | / |
| Zhimu (Rhizoma Anemarrhenae) | / | 30.2% | / | / | / | 31.3% | / |
| Chaihu (Radix Bupleuri) | / | / | 64.1% | / | / | / | 23.1% |
| Zhizi (Fructus Gardeniae) | / | / | 53.8% | / | 27.6% | / | / |
| Zexie (Rhizoma Alismatis) | / | / | 23.1% | 27.3% | / | / | / |
| Zhenzhumu (Concha Margaritifera) | / | / | 23.1% | / | / | / | 46.2% |
| Shichangpu (Rhizoma A. Tatarinowii) | / | / | / | / | / | 56.3% | 46.2% |
| Longchi (Dens Draconis) | / | / | / | / | / | 50.0% | 30.8% |
| Huangqi (Radix Astragali) | 50.0% | / | / | / | / | / | / |
| Ginger (Rhizoma Zingiberis) | 20.4% | / | / | / | / | / | / |
| Longyanrou (Arillus Longan) | 31.5% | / | / | / | / | / | / |
| Muxiang (Radix Aucklandiae) | 31.5% | / | / | / | / | / | / |
| Huangbo (Cortex Phellodendri) | / | 20.9% | / | / | / | / | / |
| Ejiao (Colla C asini) | / | 41.9% | / | / | / | / | / |
| Longdancao (Radix Gentianae) | / | / | 35.9% | / | / | / | / |
| Yujin (Radix Curcumae) | / | / | 33.3% | / | / | / | / |
| Danpi (Cortex Moutan) | / | / | 23.1% | / | / | / | / |
| Huangqin (Radix Scutellariae) | / | / | 28.2% | / | / | / | / |
| Shudihuang (Radix Rehmanniae Praeparata) | / | / | / | 27.3% | / | / | / |
| Dannanxing (Rhizome Arisaematis) | / | / | / | / | 27.6% | / | / |
| Chenpi (Pericarpium C. Reticulatae) | / | / | / | / | 44.8% | / | / |
| Zhuru (Caulis Bambusae in Taeniam) | / | / | / | / | 58.6% | / | / |
| Zhishi (Fructus A. immaturus) | / | / | / | / | 41.4% | / | / |
| Lime-water processed banxia (Rhizoma Pinelliae Preparatum) | / | / | / | / | 44.8% | / | / |
| Renshen (Radix Ginseng) | / | / | / | / | / | 25.0% | / |
| Hupo (Succinum) | / | / | / | / | / | 37.5% | / |
| Chuanxiong (Rhizoma Chuanxiong) | / | / | / | / | / | 25.0% | / |
| Longgu (Fossilia Ossis Mastodi) | / | / | / | / | / | / | 23.1% |
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