Meta-Analysis of Randomized Controlled Trials on the Efficacy of Di’ao Xinxuekang Capsule and Isosorbide Dinitrate in Treating Angina Pectoris

Table 4

Metaregression of basic characteristics of RCTs and ORs of SYMPTOMS and ECG outcomes.

Log OR	No. of RCTs	No. of participants	Factor tested	Coefficient	𝑡	𝑃
			Publication year	0.0200	0.43	0.685
			No. of authors	−0.2106	−1.63	0.165
			Trail date	0.5646	1.00	0.365
SYMPTOMS	7	550	Sample size	0.0069	1.52	0.190
			Comparable	−0.6369	−1.38	0.227
			AEs	−0.4280	−0.89	0.412
			M score	−0.4829	−1.56	0.180
			Publication year	0.0097	0.26	0.809
			No. of authors	−0.1796	−1.46	0.239
			Trail date	0.4354	0.83	0.469
ECG	5	370	Sample size	0.0073	1.10	0.354
			Comparable	−0.3195	−0.64	0.565
			AEs	−0.0911	−0.16	0.886
			M score	−0.4354	−0.83	0.469

Metaregression was conducted by residual (restricted) maximum likelihood (REML) with Knapp-Hartung modification.