Herbal Compound “Songyou Yin” Renders Hepatocellular Carcinoma Sensitive to Oxaliplatin through Inhibition of Stemness
Figure 2
SYY exhibited no significant cytotoxicity in HCC cell lines but increased their sensitivity to oxaliplatin: (a) MHCC97H cells treated with 2 mg/mL and 4 mg/mL SYY demonstrated no increase in LDH release indicating no acute cytotoxicity and (b) MHCC97H and Hep3B cell lines treated with 2 mg/mL SYY for 4 weeks showed increased chemosensitivity to oxaliplatin compared with parental cell lines.