Effects of Extracts from Trifolium medium L. and Trifolium pratense L. on Development of Estrogen Deficiency-Induced Osteoporosis in Rats
Figure 2
Effects of Trifolium medium L. (TM) and Trifolium pratense L. (TP) extracts on the strength of the femoral neck in ovariectomized (OVX) rats. The lyophilized extracts from TM or TP at doses corresponding to 10 and 20 mg/kg of isoflavone aglycones daily (TM10, TP10 and TM20, TP20, resp.), or estradiol (0.2 mg/kg daily), were administered orally to OVX rats for 4 weeks. Results are presented as the mean SEM ( = 9-10). One-way ANOVA followed by Duncan’s test was used for evaluation of the significance of the results, *.**, ***—significantly different from sham-operated control rats (SHAM).
