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Evidence-Based Complementary and Alternative Medicine
Volume 2012 (2012), Article ID 923153, 6 pages
http://dx.doi.org/10.1155/2012/923153
Research Article

Impact of Transcendental Meditation on Left Ventricular Mass in African American Adolescents

1Department of Pediatrics, Georgia Prevention Institute, Georgia Health Sciences University, HS1640, Augusta, GA 30912-3710, USA
2Colleges of Nursing and Medicine, Medical University of South Carolina, Room 418, 99 Jonathan Lucas Street, Charleston, SC 29425, USA

Received 14 October 2011; Revised 13 February 2012; Accepted 23 March 2012

Academic Editor: Ka Kit Hui

Copyright © 2012 Vernon A. Barnes et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. An early sign of ventricular remodeling is increased left ventricular mass (LVM) which over time may lead to left ventricular hypertrophy, the strongest predictor of cardiovascular morbidity and mortality, other than advancing age. Methods. 62 (30 TM; 32 CTL) African American adolescents (age 1 6 . 2 ± 1 . 3 years) with high normal systolic BP were randomly assigned to either 4-month Transcendental Meditation (TM) or health education control groups. The echocardiographic-derived measure of LVM index (LVMI = LVM/ht2.7) was measured before and after the 4-month TM study and at 4-month followup. 2D-guided M-mode echocardiography using a Hewlett Packard 5500 echosonograph was used to determine LVMI. Results. The TM group exhibited a greater decrease in LVMI at 4-month followup compared to the CTL group (−2.6 versus +0.3 gm/ht2.7, 𝑃 < 0 . 0 4 ). The TM group exhibited a lesser increase in BMI at 4-month follow-up compared to the CTL group ( 0 . 2 ± 1 . 6 versus 1 . 1 ± 1 . 4 , 𝑃 < 0 . 0 3 ). Conclusion. These findings indicate that among a group of prehypertensive African American adolescents, 4 months of TM compared to heath education resulted in a significant decrease in LVMI, and these changes were maintained at 4-month follow-up.