Zerumbone, a Southeast Asian Ginger Sesquiterpene, Induced Apoptosis of Pancreatic Carcinoma Cells through p53 Signaling Pathway

Figure 4

Effects of zerumbone on the caspase-3 activity and the generation of ROS production of PNAC-1 cells. (a) Zerumbone increased the caspase-3 activity of PANC-1 cells. 𝑛=3 independent experiments. (b) Zerumbone 30 μM increased the fluorescence density of ROS. Zerumbone increased the ROS generation in a concentration-dependent manner. 𝑛=4 independent experiments, ^∗𝑃<0.05 versus Control.

(a)

(b)