Resveratrol Produces Neurotrophic Effects on Cultured Dopaminergic Neurons through Prompting Astroglial BDNF and GDNF Release
Figure 1
Resveratrol produced neurotrophic effects on cultured DA neurons. Rat primary midbrain neuron-glia cultures were treated with different concentration of resveratrol on the first day. Seven days later, the neurotrophic effects were determined by [] DA uptake assay (a) and TH-positive neuron counting using the immunocytochemical analysis (b). Representative images of immunostaining 7 days after resveratrol treatment from three experiments were shown (c). Scale bar, 200 m. Results were expressed as a percentage of the control cultures and were the mean ± SEM from three independent experiments performed in triplicate. compared with the control cultures.
