Research Article

Toxicity of a Novel Herbomineral Preparation Las01 on Human Cancer Cell Lines and Its Safety Profile in Humans and Animals

Table 1

Effect of acute administration of Las01 in rats.

Parameters Control Las01
Group 1 Group 2 Group 3

Total WBCcount × 103 mm3
6293 ± 488
6342 ± 422
6321 ± 230
6234 ± 230
Haemoglobin (gm%)
11.91 ± 1.85
11.82 ± 1.33
11.75 ± 1.0
11.82 ± 1.0
Bilirubin total (mg/dL)
0.31 ± 0.13
0.30 ± 0.12
0.31 ± 0.15
0.32 ± 0.15
Bilirubin direct (mg/dL)
0.24 ± 0.32
0.29 ± 0.27
0.25 ± 0.25
0.27 ± 0.15
SGPT (U/L)
44.8 ± 11.5
45.7 ± 11.1
44.53 ± 12.38
46.11 ± 12.38
SGOT (U/L)135.4 ± 19.6139.3 ± 15.26136.2 ± 17.25133.4 ± 17.25
ALP (U/L)161.8 ± 92.1168.6 ± 93.2170.7 ± 94.5163.6 ± 91.5
Albumin (mg/dL)3.53 ± 0.413.35 ± 0.463.71 ± 0.323.47 ± 0.32
Globulin (mg/dL)4.03 ± 0.194.03 ± 0.364.00 ± 0.394.12 ± 0.39
Total protein (gm%)7.56 ± 0.287.38 ± 0.227.71 ± 0.427.59 ± 0.42
BUN (mg/dL)66.58 ± 7.4563.13 ± 6.666.26 ± 7.4865.32 ± 7.48
Creatinine (mg/dL)0.45 ± 0.050.46 ± 0.040.44 ± 0.040.44 ± 0.04
Sodium (mEq/L)
146 ± 4.41147.5 ± 2.82144.3 ± 5.6148.3 ± 5.6
Potassium (mEq/L)
4.15 ± 0.184.12 ± 0.394.14 ± 0. 234.16 ± 0. 23
Chloride (mEq/L)104 ± 1.18103 ± 1.68101.8 ± 3.70102.9 ± 3.70