Cucurbitacin E Induces G2/M Phase Arrest through STAT3/p53/p21 Signaling and Provokes Apoptosis via Fas/CD95 and Mitochondria-Dependent Pathways in Human Bladder Cancer T24 Cells
Figure 7
The effects of cucurbitacin E on the apoptosis-associated proteins in T24 cells. Cells (/well) seeded into 6-well plates were treated with 1000 nM cucurbitacin and were treated with different concentrations of cucurbitacin E for 48 h and then harvested for western blotting to examine the protein levels of cytochrome c, Apaf-1, BID, and truncated BID (a), Fas and FasL (b) as described in Materials and Methods.
