Research Article
Salvianolic Acid B Inhibits ERK and p38 MAPK Signaling in TGF-1-Stimulated Human Hepatic Stellate Cell Line (LX-2) via Distinct Pathways
Table 1
The changes of Col. I in LX-2 cell culture supernatants following inhibition of ERK and Smad4 signaling pathways.
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The levels of Col. I protein were determined by ELISA kit as indicated. Results were expressed as mean ± SE of three independent experiments performed in triplicate. ##Significant difference versus Control, Negative control, and SRV4 (, ); ▲▲Significant difference versus SRV4 and TGF (, ); **Significant difference versus SM4 + TGF (, ); ♦♦Significant difference versus SM4 + TGF + SA-B, SM4 + TGF + PD, and TGF + SA-B + PD (, ). |