Korean Red Ginseng Suppresses Metastasis of Human Hepatoma SK-Hep1 Cells by Inhibiting Matrix Metalloproteinase-2/-9 and Urokinase Plasminogen Activator

Figure 5

Effect of WKRG on wound healing migration of SK-Hep1 cells. Wound was introduced by scraping the confluent cell monolayer with a pipette tip. (a) Representative photographs of SK-Hep1 cells that received either control or WKRG treatments (0, 100, 200, and 400 μg/mL) for 0, 12 and 24 h. (b) Migrated cells across the black lines were counted in six random fields for each treatment. Quantitative assessment of the number of cells in the denuded zone is expressed as the mean ± SD of three independent experiments. *𝑃<0.05, **𝑃<0.01, and ***𝑃<0.001 as compared with the untreated control.

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