Karyotype and DNA-Methylation Responses in Myelodysplastic Syndromes following Treatment with Traditional Chinese Formula Containing Arsenic
Table 4
Functions of genes with hypermethylation after treatment.
Go_id
Go_name
Diffgene _count
value
FDR
GO:0007596
Blood coagulation
13
GO:0007088
regulation of mitosis
3
GO:0016337
Cell-cell adhesion
5
GO:0006357
Regulation of transcription from RNA polymerase II promoter
8
GO:0006325
Chromatin organization
3
GO:0006890
Retrograde vesicle-mediated transport, Golgi to ER
3
GO:0032312
Regulation of ARF GTPase activity
2
GO:0033690
Positive regulation of osteoblast proliferation
2
GO:0060710
Chorioallantoic fusion
2
GO:0006364
rRNA processing
4
GO:0043069
Negative regulation of programmed cell death
2
GO:0015031
Protein transport
9
GO:0005975
Carbohydrate metabolic process
8
GO:0006355
Regulation of transcription, DNA-dependent
20
GO:0007155
Cell adhesion
11
GO:0042953
Lipoprotein transport
2
GO:0048863
Stem cell differentiation
2
GO:0009395
Phospholipid catabolic process
2
This table shows functions of genes with hypermethylation after treatment. go_id: gene ID number in Gene Ontology database; go_name: category of function of gene; diffgene_count: number of gene methylated; value: indicating methylation is significant; FDR: false discovery rate, as filter cutoff rate.