Table 2: The regulation of transcription factors related to lipid metabolism by TCM.

Herb/ingredientsPPAR-α/γ/δLXR-αSREBPsFXROthersReference

Berberineα(+), (+)SRE1Insig-i(+), CPTIA[23, 3638, 50]
Curcumin (+)[25, 26]
Danshen/dihydrotanshinone 1, salvianolic acid, and Danshensu rosmarinic acidα(+)(+)−1c()(+)ABCA1, ABCB4/11, SHP(+)[40, 41]
Ginsengα(+)[45]
Gynostemma pentaphyllum/gypenosideα(+)[43]
Resin of the guggul tree/guggulsterone()AR/GR/MR(); PR/ERα(+)[44]
Ligustrum lucidum/oleanolic acidα(+), (+)protein kinase B (+)[51]
Hawthorn, hawthorn-flavoneα(+)[11, 24]
Morronisideα(+)−1();2() NF-kβ, iNOS, ()[52]
FTZα(+)() [49]
Fenugreek (TEFS) ()−1()cEBP-α()[42]

Notes for tables: (+): positive/upregulation; (−) negative/downregulation.