Research Article

Rutin, a Flavonoid That Is a Main Component of Saussurea involucrata, Attenuates the Senescence Effect in D-Galactose Aging Mouse Model

Figure 6

Effects of rutin (30 mg/kg) on the step-through latencies in rats. The control group received subcutaneous (s.c.) injections of phosphate-buffered saline. The aged group received D-galactose (300 mg/kg, s.c.). SI-2 + G-gal or rutin + G-gal groups received D-galactose (300 mg/kg/day, s.c.) plus SI-2 or rutin (30 mg/kg/day, p.o.). Treatments were administered for 6 weeks. Retention tests were performed one, two, and seven days after training, * , ** , and compared to the same day control, Tukey-Kramer’s test. Values are expressed as means ± SEM.
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