Alternative Pathways of Cancer Cell Death by Rottlerin: Apoptosis versus Autophagy
Figure 3
Rottlerin induced the cytoplasmic accumulation of multiple vacuole-like structures in cells. (a) Light microscopy images of Toluidine blue-stained cells; (b) phase contrast microscopy; (c) transmission electron microscopy images after a 24 h exposure to 20 μM Rottlerin; control was treated with DMSO alone; o.m.: original magnification. Representative of three independent experiments.
