Catenarin Prevents Type 1 Diabetes in Nonobese Diabetic Mice via Inhibition of Leukocyte Migration Involving the MEK6/p38 and MEK7/JNK Pathways
Figure 3
Effect of catenarin on expression level of CCR5 or CXCR4 (a). JK-EF1α-CCR5 cells were incubated with vehicle or catenarin (1 μg/mL) for 1 h. The cells were stained with FITC-conjugated anti-CCR5 Ab or isotype Ab plus FITC-conjugated secondary Ab. Expression level of CCR5 was indicated by fluorescence intensity. The data are representative of 4 independent experiments. (b) The same procedure was followed as in (a) except that Jurkat cells and anti-CXCR4 Ab were used.
