Research Article

Cornel Iridoid Glycoside Attenuates Tau Hyperphosphorylation by Inhibition of PP2A Demethylation

Figure 4

CIG does not alter the phosphorylation level of GSK- and AKT. SK-N-SH cells were exposed to 10 μM WT/GFX for 3 h after the incubation with CIG (50, 100, and 200 μg/mL) for 24 h. ((a), (b)) Western blotting analysis of the levels of phosphorylated Akt at Ser473 and total Akt; ((c), (d)) western blotting analysis of the levels of phosphorylated GSK- at Ser9 and GSK- . GAPDH was used as an internal control. The level of control group was set as 100%. Data were expressed as the mean ± SD of 3 experiments. versus control group.
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(a)
108486.fig.004b
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(c)
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(d)