Induction of Apoptosis by Luteolin Involving Akt Inactivation in Human 786-O Renal Cell Carcinoma Cells

Figure 8

possible signaling cascade of apoptosis elicited by luteolin in 786-O cells is proposed. This schematic diagram indicates the signaling molecules employed in mediating 786-O cell apoptosis after luteolin treatment. Some additional signaling molecules and cascades have been omitted for the sake of clarity.