Hypoglycemic Activity and Antioxidative Stress of Extracts and Corymbiferin from Swertia bimaculata In Vitro and In Vivo

Table 2

Effects on serum lipid and insulin levels in diabetic rats.

Groups	TC (mmol/L)	TG (mmol/L)	LDL (mmol/L)	HDL/LDL	Insulin (mU/L)
Normal	1.70±0.07^∗∗	0.79±0.08^∗	0.24±0.02	6.80±0.52	7.81±0.28^∗
Diabetic	2.42±0.07	1.35±0.15	0.45±0.02	4.46±0.20	3.97±0.14
Metformin	2.27±0.14	0.99±0.18	0.31±0.03^∗∗	6.79±0.88	4.86±0.17^∗
ETH (400 mg/kg)	2.31±0.12	1.02±0.20	0.32±0.03^∗∗	7.35±0.65	4.2±0.19
ETH (200 mg/kg)	1.91±0.12^∗	0.84±0.08^∗	0.24±0.02^∗∗	8.03±0.80^∗	4.47±0.20
DTH (400 mg/kg)	2.00±0.15	0.59±0.10^∗∗	0.26±0.08^∗∗	7.72±0.76^∗	4.80±0.24^∗
DTH (200 mg/kg)	1.72±0.09^∗∗	0.51±0.06^∗∗	0.20±0.01^∗∗	8.28±0.31^∗∗	4.69±0.18^∗
Corymbiferin	1.96±0.16^∗	0.56±0.06^∗∗	0.24±0.03^∗∗	9.29±1.26^∗∗	4.81±0.31^∗

Data were shown as the means ± S.E.M. ^∗𝑃<0.05, ^∗∗𝑃<0.01 compared to diabetic group.