Hypoglycemic Activity and Antioxidative Stress of Extracts and Corymbiferin from Swertia bimaculata In Vitro and In Vivo

Table 3

Effects on CAT, GSH, GPx, SOD, and MDA from liver tissues.

Groups	CAT (U/mg protein)	GSH (nmol/mg protein)	GPx (unit)	SOD (U/mg protein)	MDA (nmol/mg protein)
Normal	40.32±3.30^∗∗	412.49±20.03^∗∗	399.21±22.33^∗∗	166.59±16.50^∗∗	1.28±0.37^∗∗
Diabetic	16.59±4.05	246.40±6.73	292.34±23.71	117.56±6.84	2.80±0.80
Metformin	33.64±6.00^∗∗	326.64±11.52^∗∗	336.30±15.70	140.71±5.47^∗∗	1.49±0.27^∗∗
ETH (400 mg/kg)	24.01±6.29	337.69±9.23^∗∗	295.38±9.04	133.03±7.48^∗∗	1.46±0.33^∗∗
ETH (200 mg/kg)	26.39±4.78^∗∗	357.73±11.85^∗∗	340.31±27.01	141.14±4.83^∗∗	1.36±0.19^∗∗
DTH (400 mg/kg)	28.32±5.57^∗∗	369.24±18.23^∗∗	352.80±8.12^∗	138.49±12.48^∗∗	1.11±0.15^∗∗
DTH (200 mg/kg)	25.91±5.65^∗∗	366.05±25.18^∗∗	320.17±12.72	126.76±11.25	1.22±0.21^∗∗
Corymbiferin	26.45±5.20^∗∗	297.66±4.63^∗	431.88±13.36^∗∗	136.67±16.30^∗∗	1.06±0.10^∗∗

Data are shown as the means ± S.E.M. ^∗𝑃<0.05, ^∗∗𝑃<0.01 compared to diabetic group.