Hypoglycemic Activity and Antioxidative Stress of Extracts and Corymbiferin from Swertia bimaculata In Vitro and In Vivo

Table 4

Effects on glycogen, GK, and G6Pase in diabetic rats.

Groups	Liver
	Glycogen (mg/g tissue)	GK (mU/mg protein)	G6Pase (mU/mg protein)
Normal	8.60±2.15^∗∗	106.30±7.67^∗∗	365.67±24.89^∗∗
Diabetic	4.82±1.13	81.12±9.47	454.15±64.81
Metformin	7.32±1.25^∗	95.23±7.31^∗∗	388.00.±43.64^∗
ETH (400 mg/kg)	6.15±0.85	90.94±6.40	401.54±61.32
ETH (200 mg/kg)	6.85±1.82^∗	89.58±11.50	391.59±40.67^∗
DTH (400 mg/kg)	7.21±2.41^∗	94.95±7.80^∗∗	378.93±55.13^∗∗
DTH (200 mg/kg)	7.06±1.19^∗	94.00±9.22^∗	379.47±55.39^∗∗
Corymbiferin	7.59±3.25^∗∗	104.27±10.18^∗∗	381.75±54.09^∗∗

Data were shown as the means ± S.E.M. ^∗𝑃<0.05, ^∗∗𝑃<0.01 compared to diabetic group.