Sulforaphane Attenuates Gentamicin-Induced Nephrotoxicity: Role of Mitochondrial Protection

Figure 10

SFN treatment prevents the GM-induced protein nitration in renal cortex. Representative figures are shown in (b–e) and the isotype control is shown in (a). The immunoprevalence of 3-NT in the (d) GM group is higher when it is compared to (e) SFN + GM, (b) CT, and (c) SFN groups. This is mainly expressed in tubular cells and the parietal epithelium of Bowman (40x). (f) Quantification shows that SFN entirely prevents GM-induced protein nitration. Data are mean±SEM. ^∗𝑃<0.05 versus CT; ^#𝑃<0.05 versus GM.

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